World Health Organization (WHO) declared a global public health emergency due to the recent spread of COVID-19 throughout the world. Millions of people are affected daily and thousands died. Almost all countries are now paying attention to control this pandemic outbreak. Therefore, researchers are trying to identify the pathophysiology of the disease, appropriate prognosis, effective management and prevention of COVID-19. Based on current published evidence, this review article specifies the role of different nutrients in the possible prevention and management of COVID-19 and viral infections. Balanced nutrition including adequate vitamin C, vitamin A, vitamin D, magnesium, selenium, zinc and phytonutrients have shown promising immune-boosting roles in COVID-19 and other respiratory infections due to their potential anti-inflammatory and antioxidants properties. These micronutrients act against COVID-19 infections both individually and synergistically.