The available treatments of metabolic alkalosis should be given in the hospital and may be associated with serious adverse events. We aimed to use rice broth for treatment of metabolic alkalosis. Patients with metabolic alkalosis were received oral rice broth solution; serum electrolytes and acid-base parameters were measured before and after the treatment. The majority of patients were older and in the ICU. After treatment with rice broth solution, there was statistical significant decreased in blood PH and serum [HCO3-] from a mean of 7.45 ± 0.03 to 7.4 ± 0.009 and 34.5 ± 4.4 to 24.9 ± 1.1 mmol/l respectively and statistical significant increase in serum [Na+], serum [Cl-], serum [K+], serum [Ca+2], serum [PO4-2] and serum [Mg+2] from a mean of 132.5 ± 3.7 to 136.5 ± 1.9 mmol/l, 93.2 ± 5.4 to 101.9 ± 2.7 mmol/l, 3.1 ± 0.3 to 3.6 ± 0.2 mmol/l, 0.99 ± 0.1 to 1 ± 0.1mmol/l, 3.4 ± 0.5 to 3.6 ± 0.4 mg/dl and 1.88 ± 0.2 to 2.28 ± 0.17 mg/dl respectively. Rice broth is an effective oral treatment of metabolic alkalosis.