Insulin resistance is considered as one of the significant causes of morbidity and mortality as it might develop diabetes, heart, and renal diseases. To investigate the prevalence of Insulin resistance in the Makkah region in Saudi Arabia and the related risk sociodemographic Method: An online valid questionnaire was collected from a random sample of only Saudi 1514 adults; non-Arabic speakers and non-Saudi were excluded. The related sociodemographic data was gathered. The insulin resistance risk score was conducted using a non-invasive easy scoring system based on Lindstrom and Tuomilehto's study18. In total, 70% of the sample had a lower risk level, and only about 14% with higher risk compared to 16% with no risk. Individuals at a higher risk of insulin resistance were males, with high-income levels (≤10,000SR) and elementary education. The most common risk of insulin resistance was at a moderate risk level for males with high income and lower education levels.